Pure Mana CBD Full Spectrum CBD Oil
As scientists around the world race to find a solution to the ongoing COVID-19 pandemic, CBD has emerged as a promising research candidate. It’s already known for mitigating many COVID-19 symptoms as well as helping to keep the immune response under control. Preliminary results also indicate that CBD and its ‘entourage effect’ may even help stop the virus at a cellular level.
Here’s what we know so far about CBD’s effects on COVID-19.
WHAT IS CBD?
Cannabidiol (CBD) is an organic chemical made by the cannabis plant. There are over 22,700 published studies on cannabis, and it has proven to be effective for many physical and mental health conditions.
CBD has a high safety and tolerability profile with no known harmful side effects. Unlike THC, cannabis’ flashiest active compound, CBD has no psychotropic effects and won’t induce a ‘high.’
CBD VS COVID-19
CBD’s main superpower is helping to keep your internal systems running smoothly and in perfect balance. The healthier and more stabilized you are in the first place, the better your body will be at keeping COVID-19 and its symptoms at bay.
CBD is also highly effective at fighting symptoms like pain and nausea. It stimulates the production of anandamide - the ‘bliss cannabinoid’ - in your brain, which calms your screaming nervous and digestive systems and helps you relax.
In addition to addressing and managing the symptoms, CBD is known for finding and soothing the root cause of health issues. This is especially important for diseases like COVID-19, which can instigate dangerous cycles of escalating inflammation levels caused, not by the virus itself, but by a runaway immune system.
CBD helps regulate your immune system. It’s a major factor in keeping your immunity strong and balanced so that your systems stay prepared in case of a COVID-19 attack.
Antiviral medication stimulates your immune response. Autoimmune medication stifles it. CBD has the ability to do both things and change its actions depending on what your body needs. This results in a targeted, effective approach to each threat, instead of the immune system’s typical reaction of raining fire on both healthy and unhealthy cells.
One of COVID-19’s most damaging problems is the pro-inflammatory cytokine storm. This happens when an unfamiliar attacker triggers an overzealous counter strike from your immune cells. The runaway response can feel like inflammation of your airways, a high fever, and way too much mucus in your lungs.
CBD is famous for its anti-inflammatory properties. It’s especially helpful in cases where the immune system is running wild with cytokines, creating more cytokines and inflammation triggering more inflammation. CBD seems to know how to quiet down an overactive immune system and interrupt patterns of inflammation escalation.
Although there still isn’t much data on the specific interaction of CBD and COVID-19, there have been many studies on CBD’s effect on similar inflammatory responses caused by other diseases.
THE RESEARCH ON CBD VS INFLAMMATION
• In mouse models of lung injury, CBD reduced lipopolysaccharide-induced acute pulmonary inflammation.
• In piglets with hypoxic-ischemic lung damage, CBD reduced histologic damage, decreased leukocyte infiltration and modulated IL-1 concentration in bronchoalveolar lavage fluid.
• CBD has a direct suppressive effect on T-cell secretion of inflammatory serums IL-1 and IFN?.
• In mouse models of experimental asthma, CBD treatment reduced airway inflammation, as well as levels of IL-4, IL-5, IL-13, IL-6 and TNF-?, which are implicated in airway inflammation.
• In studies on humans, cannabinoid use prevented induction of pro-inflammatory CD16+ monocytes and production of IP-10, suggesting anti-inflammatory effects in humans.
Although the emerging research is far from conclusive, there is evidence indicating CBD can help block COVID-19’s entry into your body.
Viruses can’t survive for very long on their own. They need a host cell that they can break into and infect so they can start reproducing. For SARS-CoV-2, the virus that causes COVID-19, the main way it gains access to your cells is via a receptor protein called an "angiotensin-converting enzyme II," or ACE2.
You have ACE2 ‘gateways’ in cells all over your body. This includes your lung tissue, heart, kidneys, and intestines. The virus can use its spike protein to bind to these particular receptors and break through the cell membrane.
A 2020 study by Canadian researchers found that certain strains of cannabis high in CBD can modulate the expression of the ACE2 gene as well as the level of ACE2 protein in a cell membrane. The belief is that keeping ACE2 levels low in gateway tissues may reduce the cell’s vulnerability to COVID-19.
Terpenes are organic compounds made by plants and some insects. They’re what give many plants their distinctive aromas and flavors. If you’ve ever been close to a cannabis plant, you probably know what cannabis terpenes smell like.
Many terpenes also have therapeutic benefits. They’re usually described as part of the ‘entourage effect’ of cannabis, where the various terpenes, cannabinoids, and other organic compounds work together synergistically and in harmony.
Although there are no specific studies yet on terpenes and COVID-19, there are some very interesting results from previous studies of the effects of essential oils on similar coronaviruses. Certain terpenes found in essential oils have demonstrated inhibitory effects on SARS-CoV, the COVID-19 virus’ precursor, as well as HSV-1 and other coronaviruses.
In a curious twist, two of the terpenes the researchers looked at are also found in full spectrum CBD oil. These terpenes, beta-myrcene and alpha-pinene, may give CBD additional preventative properties against COVID-19.
In order to get the full terpene effect, it’s important to use high-quality full spectrum or broad spectrum CBD oil, not just CBD isolate. Full spectrum and broad spectrum CBD oils are made from the entire hemp plant and contain blends of cannabinoids and terpenes, which improve the therapeutic properties.
THE RESEARCH ON TERPENES VS CORONAVIRUSES
• L. nobilis oil exerted an interesting activity against SARS-CoV with an IC(50) value of 120 microg/ml and a selectivity index (SI) of 4.16.
• This oil was characterized by the presence of beta-ocimene, 1,8-cineole, alpha-pinene, and beta-pinene as the main constituents.
• J. oxycedrus ssp. oxycedrus oil, in which alpha-pinene and beta-myrcene were the major constituents, revealed antiviral activity against HSV-1 with an IC(50) value of 200 microg/ml and a SI of 5.
CBD’s most promising properties in the fight against COVID-19 are its immunomodulatory effects. It helps restore balance in your immune system and down-regulate inflammatory cytokine production. It can also help alleviate many symptoms of COVID-19, and may even be able to deny the virus passage through your cell walls.
More research is needed to understand CBD’s antiviral properties and how they affect the human body. However, its positive effects on the immune system and general homeostasis is well-established in medical science.
If you decide to take CBD to support your health and immune system, make sure to only use high quality CBD oil made from organically grown hemp plants.
OUR TOP CBD PICKS
Pure Mana CBD is made with the very best growing and manufacturing processes, and each batch is 3rd party lab tested. Additionally, all their CBD products are nano-amplified - a process that increases the bioavailability (absorption rate) of the CBD by 65-90%. This means you get the fastest-acting, longest-lasting, most potent results from every dose.
Pure Mana’s full spectrum and broad spectrum CBD oils come with the additional protective entourage effects of terpenes and other complementary cannabinoids. They also offer an “Immune Stack” with CBD and other essential nutrients designed to boost your immune system and keep you healthy during these uncertain times.